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Image Search Results
Journal: Scientific Reports
Article Title: Umbilical cord serum metabolomics identifies amino acid alterations associated with impaired linear growth in small for gestational age infants
doi: 10.1038/s41598-025-12856-0
Figure Lengend Snippet: Metabolomic differences between the SGA and AGA groups.( A ) Score plot of an orthogonal partial least-squares discriminant analysis (OPLS-DA) comparing metabolomic profiles between the small for gestational age (SGA) and appropriate for gestational age (AGA) groups (SIMCA ver. 13.0.3.0, Umetrics). ( B ) S-plot showing metabolites contributing to group separation; significant metabolites were identified based on |p(corr)|> 0.6 (SIMCA). ( C ) Variable importance in projection (VIP) score plot showing metabolites with VIP > 1 (SIMCA; visualized using GraphPad Prism ver. 10, GraphPad Software). ( D ) Volcano plot identifying metabolites with p < 0.05 (MetaboAnalyst 6.0). ( E – J ) Receiver operating characteristic (ROC) curves for representative metabolites identified as significant in at least two of the three analyses (S-plot, VIP score, and volcano plot) (GraphPad Prism ver. 10). ( K ) Pathway enrichment analysis performed using MetaboAnalyst 6.0.
Article Snippet: The integral metabolomics datasets were imported into the
Techniques: Software
Journal: Scientific Reports
Article Title: Umbilical cord serum metabolomics identifies amino acid alterations associated with impaired linear growth in small for gestational age infants
doi: 10.1038/s41598-025-12856-0
Figure Lengend Snippet: Distinct metabolic profiles between the SGA-tall and SGA-short groups.( A ) Score plot of an orthogonal partial least-squares discriminant analysis (OPLS-DA) comparing metabolomic profiles between the SGA-tall and SGA-short groups (SIMCA ver. 13.0.3.0, Umetrics). ( B ) S-plot showing metabolites contributing to group separation; significant metabolites were identified based on |p(corr)|> 0.6 (SIMCA). ( C ) Variable importance in projection (VIP) score plot showing metabolites with VIP > 1 (SIMCA; visualized using GraphPad Prism ver. 10). ( D ) Volcano plot identifying metabolites with p < 0.05 (MetaboAnalyst 6.0). ( E – H ) Receiver operating characteristic (ROC) curves for representative metabolites identified as significant in at least two of the three analyses (GraphPad Prism ver. 10). ( I ) Pathway enrichment analysis performed using MetaboAnalyst 6.0.
Article Snippet: The integral metabolomics datasets were imported into the
Techniques: